Whereas reduced-count MBL rarely progresses to CLL, higher-count MBL progresses to CLL demanding therapy at a fee of 1% to two% per annum. Significant-rely MBL is distinguished from Rai 0 CLL based upon if the B-cell depend is over or beneath five × 109/L. Whilst people today with both of those high-depend MBL and CLL Rai phase 0 are at enhanced c